･There was a significant negative correlation between the attendance rate and the reduction of regional cerebral blood flow (CBF) in the right parietal region. The significant negative correlation suggests that these non-pharmacological interventions ameliorated the reduction of CBF over time.
･Our program may prevent the vulnerability of the parietal region to neurodegeneration induced by amyloid β-protein accumulation.
･Our results would suggest that the important point of the CIDC program was not the number of attendances but efficient attendance.
