マウスにおけるREM睡眠の開始には、扁桃体基底外側核における一過的なドーパミンシグナルが重要である

・Transient dopamine elevation in the basolateral amygdala during NREM sleep plays an important role in triggering NREM-REM sleep transition.
・DRD2-expressing neurons in the basolateral amygdala activate the amygdala in response to dopamine, and this activation leads to REM sleep.
・Transient dopamine elevation in the basolateral amygdala during wakefulness is seen in narcoleptics, and plays an important role in triggering cataplexy.

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